Strengthening bones through
bioavailability
By Jeff Leach
Osteoporosis.
Just saying the word makes my bones ache. If you’re a woman over the
age of 50, you have about 40% chance of suffering from an osteoporotic
fracture. That’s higher than your risk of contracting breast and
ovarian cancer. Even worse, 50% of the osteoporotic hip-fracture
patients never fully regain independence and more than 20% will die
within 6 months. Not good odds.
If
you are someone who thinks osteoporosis is a “women’s disease,”
think again. It affects 25% of men over the age of 50 and an alarming
number of young people. If the current trends continue, the problem is
expected to worsen by 60% in the next 20 years – regardless of gender.
Most
folks are aware that osteoporosis is characterized by bone fragility and
related to dietary intake of calcium, or the lack thereof. Simply put
– calcium is used to build bones and to a lesser extent, teeth. From
the time we are born until our mid twenties, our bones are continually
growing and require calcium to do so. The goal during this critical
growth period is to achieve peak bone mass. Thick, mineral dense bones.
Your
peak bone mass – which again, you can only control until your mid
twenties – will strongly influence your risk of osteoporosis later in
life.
From
our mid twenties to about age 50, the density of our bones is relatively
stable. This means no matter how much calcium you consume, your bones
are not going to get any denser. The goal now is to maintain the bone
mass you developed in youth and minimize bone loss associated with
aging. This is especially important for women, who must contend with a
number of bone loss issues exaggerated during and after menopause –
not to mention the demands of pregnancy and lactation on bone health.
While
you are older and wiser, the efficiency at which your body absorbs
calcium in later years, like some many things associated with aging,
isn’t what it used to be.
Despite
the fact that we are confronted daily with the “eat more calcium”
message for “healthy bones” on TV, in newspapers and magazines, on
annoying billboards, and along the aisles of our favorite grocery store,
nearly 70% of Americans consume less than the daily recommended
allowance of 1,000 mg of calcium a day – give or take.
Our
daily intake may in fact be lower when you consider that, depending on
our particular genetic makeup and the composition of a given meal, our
bodies may only absorb 30-35% of the total calcium advertised for a
given serving. Think about that little piece of critical information for
a minute.
Calcium
that is not absorbed is mostly excreted in our urine and feces, which
brings up an important issue – and the point of why I am writing about
osteoporosis – bioavailability.
The
terms “bioavailability” and “absorption” are critical
nutritional terms that are often used incorrectly. Absorption describes
the process of transport of a mineral-like calcium from your intestine
across the intestinal mucosa (the wall) into the circulatory system, so
that it may be utilized or stored by the body. On the other hand, the
bioavailability of a mineral like calcium means the “proportion”
that is actually absorbed and thus utilized or stored.
The
key here is solubility. A swallowed penny, for example, has zero
bioavailability. It will simply enter one end and come out the other,
intact. Whereas a glass of water is highly soluble and will be easily
absorbed – nearly 100% bioavailability.
Even
though you think you are getting 500 to 1,000 mg of calcium from a given
food item, meal, or “supplement,” you may not.
Given
this piece of information, it’s not only important that we increase
our daily intake of calcium to recommended levels, we should also seek
out means to increase the bioavailability of the calcium that we do
consume so that it’s not wasted, so to speak.
One
way of doing this is to lower the pH of your gastrointestinal system by
delivering food to the trillions of tiny bacteria that live in your
colon (specifically lactic acid bacteria). And that means fiber.
Once
in the colon, fiber is broken down by resident bacteria through
hydrolysis and fermentation, which produces, among other things, short
chain fatty acids and lactic acid. These acids then in turn make the
colon more acidic, which increases the solubility of the calcium, making
it more absorbable.
One of the short chain fatty acids produced (butyrate) has been shown to
induce cell growth in the colon, which in turn increases the
“absorptive surface” of the colon. This means more calcium is
absorbed and less is excreted in feces.
Among
the hundreds of species of bacteria living in your colon, you want to
increase the number of the bifidobacteria and lactobacillus,
specifically. These two particular groups are known to be especially
useful in increasing the acidity of your colon – and they thrive well
on special inulin and oligofructose-type fibers that occur naturally in
onions, garlic, artichokes, asparagus, and in lesser amounts in
wheat-based products. They are also commercially extracted from chicory
roots (think chicory coffee) and added as a food ingredient in a growing
number of foods. These special fibers are known as prebiotics.
By
increasing the bioavailability of the calcium that we do consume through
a more acidic colon, we can add an additional dietary measure to the
preventive strategies for fighting this terrible disease.
______________
Effect of prebiotic
supplementation and calcium intake on body mass index.
J Pediatr. 2007 Sep;151(3):293-8.
Diet,
nutrition, and bone health.
J Nutr. 2007 Nov;137(11 Suppl):2507S-2512S.
An
inulin-type fructan enhances calcium absorption primarily via an
effect on colonic absorption in humans.
J Nutr. 2007
Oct;137(10):2208-12.
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